名稱:現貨訂購|Recombinant Human IL-6
貨號:200-06
規格:20ug
產地:PeproTech
Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses. It stimulates B-cell differentiation and antibody production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism.
Biological Activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of IL-6 dependent murine 7TD1 cells is ≤ 0.1 ng/ml, Recombinant human IL-6 is a 20.9 kDa protein containing 184 amino acid residues. corresponding to a specific activity of ≥ 1 x 107units/mg.
Cross Reactivity: IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6R α and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Monkey, Mouse, Rat
Description: Country of Origin: USA. IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, synergizes with IL-3 in megakaryocyte development and plaet production, IL-6 has diverse biological functions.
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