QQ交談eBioscience 14-6763-81Anti-I kappa B alpha （IKB-a） Purified 原裝現貨
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- 上海葉舟生物科技有限公司
- 2018-05-05 03:30:57
- 上海市
- 美國
- 760
【簡單介紹】
【詳細說明】
產品名稱：Anti-I kappa B alpha （IKB-a） Purified
貨號：eBioscience 14-6763-81
規格：50 ug
Anti-I kappa B alpha （IKB-a） Purified
Also known as: I Kappa Beta alpha, IKBa, IKB alpha
Clone: Polyclonal
Description: The polyclonal antibody reacts with mouse, rat, and human IkB-alpha; the antibody was raised against a peptide mapping to the carboxy terminal domain of human IkB-alpha. The NFkB family of transcription factors is sequestered in the cytoplasm by IkB inhibitory proteins （1&2）.IkB-alpha and IkB-beta are the two members of this family most often cited for their regulatory function of NFkB directed gene expression. The interaction of NFkB dimers with IkB proteins keeps the complex in the cytoplasm, but upon cellular stimulation the IkB proteins are phosphorylated and subsequently degraded （1&3）. The free NFkB can now enter the nucleus and induce gene expression of proteins critical for cellular proliferation, differentation, or apoptosis （1-4）.
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